A woman with TS is 100 times more likely to die during pregnancy than all other pregnant women. Women with TS are at a particularly high risk for developing heart vessel problems during pregnancy, specifically rupture (bursting) of the aorta (a large vessel leading from the heart). Is it safe for women with TS to become pregnant? Pregnancy is possible using donor eggs but with increased risks. Infertility is common in girls and women with TS due to rapid loss of eggs within the ovaries. How does TS affect the ability to have children? Medicine and surgery to correct heart and blood vessel defects.Estrogen to improve bone mass and strength.Estrogen to help develop secondary sexual characteristics, such as breast development, in girls with delayed puberty.Examples of some treatments available include: However, treatment strategies are available to reduce the health burden related to the diagnosis. TS is a genetic disorder and cannot be cured. Premature ovarian insufficiency (“early menopause”).Examples of health concerns associated with TS are: The number, type, and severity of health problems associated with TS are variable some women are minimally affected while others develop serious health concerns. Short stature (typically under 5 feet tall)Īre there any health problems associated with TS?.Not all girls/women will have all the characteristics. There are physical features that are common in girls/women with TS. Are there any physical traits of Turner syndrome? Having different cells with different chromosomes within the same person is called mosaicism. Other women have a single X chromosome in many of the cells of their body and two or more X chromosomes in the remaining cells.
Some females with TS have only a single complete “X” chromosome in their cells instead of the usual 2 complete X chromosomes. Karyotyping provides both a count of the number of chromosomes (bundle of genetic material) as well as information on appearance of each chromosome (normal versus abnormal). An affected baby can be diagnosed before birth by testing cells collected by amniocentesis, or placental cells collected by chorionic villus sampling. A karyotype is usually performed on blood. TS is diagnosed by chromosome analysis, also called karyotype testing. TS occurs when all or part of one of the two X chromosomes in the developing embryo is lost. TS is not related to the genetic makeup of a mother or father, but is a chance happening and cannot be passed on from either parent. About 1 in every 2,000 female babies born is affected.
Turner syndrome (TS) is an infrequent genetic disorder in females.
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